Banner image placeholder
Banner image
B
Christopher Barrett
MD

Curriculum vitae


Surgery Department

UNMC



Publications


Antibiotic use in acute mesenteric ischemia: a review of the evidence and call to action


Yuqian Tian, Sanjeev Dhara, Christopher D. Barrett, A. Richman, T. Brahmbhatt

Thrombosis Journal, 2023


PLASMINOGEN DEFICIENCY OF PLEURAL FLUID DUE TO NEUTROPHIL INFLAMMATORY PROTEASE DEGREDATION IN EMPYEMA PATIENTS: A CAUSE OF INTRAPLEURAL LYTIC FAILURE?


Christopher D. Barrett, Peter K Moore, H. Moore, Ernest E. Moore, James G Chandler, A. Sauaia, Keely Buesing, D. Hershberger, I. Douglas, Angel Augusto DR PEREZ-CALATAYUD, Michael B Yaffe

Chest, 2023


Advances in the Management of Coagulopathy in Trauma: The Role of Viscoelastic Hemostatic Assays across All Phases of Trauma Care.


J. Meizoso, Christopher D. Barrett, Ernest E. Moore, H. Moore

Seminars in Thrombosis and Hemostasis, 2022


An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.


C. Ellson, Ingred Goretti Riça, Jacob S Kim, Yu‐ming M. Huang, D. Lim, Tanya Mitra, Albert Hsu, E. Wei, Christopher D. Barrett, M. Wahl, H. Delbrück, U. Heinemann, H. Oschkinat, Chia‐en A. Chang, M. Yaffe

Journal of Molecular Biology, 2022


Illustrated State‐of‐the‐Art Capsules of the ISTH 2022 Congress


R. Ariëns, B. Hunt, E. Agbani, Josefin Ahnström, R. Ahrends, R. Alikhan, A. Assinger, Z. Bagoly, A. Balduini, Elena Barbon, Christopher D. Barrett, P. Batty, J. Carneiro, W. Chan, M. D. de Maat, Kerstin de Wit, C. Denis, M. Ellis, R. Eslick, Hongxia Fu, C. Hayward, B. Ho-Tin-Noé, F. Klok, Riten Kumar, Karin Leiderman, R. Litvinov, N. Mackman, Z. McQuilten, M. Neal, William A. E. Parker, R. Preston, J. Rayes, A. Rezaie, L. Roberts, B. Rocca, S. Shapiro, D. Siegal, L. Sousa, K. Suzuki-Inoue, T. Zafar, Jiaxi Zhou

Research and Practice in Thrombosis and Haemostasis, 2022


In Situ Pulmonary Thrombolysis and Perfusion Lung Angiography in Severe COVID-19 Respiratory Failure


Á. Pérez-Calatayud, Rocío Enríquez-García, Christian Fareli-González, Christopher D. Barrett, C. A. Saldivar-Rodea, Jorge Perulles-Marin, M. Reyes-Caldelas, Carlos Ivan Rosenberg-Contreras, J. Gómez-Moreno, G. Guerrero-Avendaño, R. Serrano-Loyola, R. Carrillo-Esper, E. Moore

Critical Care Explorations, 2022


MUlticenter STudy of tissue plasminogen activator (alteplase) use in COVID‐19 severe respiratory failure (MUST COVID): A retrospective cohort study


Christopher D. Barrett, H. Moore, Ernest E. Moore, D. Benjamin Christie, S. Orfanos, L. Anez-Bustillos, Rashi Jhunjhunwala, S. Hussain, S. Shaefi, Janice Wang, N. Hajizadeh, Elias N. Baedorf-Kassis, Ammar Al‐Shammaa, Krystal Capers, V. Banner-Goodspeed, F. Wright, T. Bull, Peter K. Moore, Hannah M. Nemec, John Thomas Buchanan, Cory Nonnemacher, Natalie Rajcooar, Ramona Ramdeo, M. Yacoub, A. Guevara, Aileen Espinal, L. Hattar, A. Moraco, R. McIntyre, D. Talmor, A. Sauaia, M. Yaffe

Research and Practice in Thrombosis and Haemostasis, 2022


Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion


H. Moore, M. Neal, M. Bertolet, Brian A. Joughin, M. Yaffe, Christopher D. Barrett, Molly A. Bird, R. P. Tracy, Ernest E. Moore, J. Sperry, B. Zuckerbraun, Myung S. Park, M. Cohen, S. Wisniewski, J. Morrissey

Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2022


Qualitative Evaluation of an Artificial Intelligence–Based Clinical Decision Support System to Guide Rhythm Management of Atrial Fibrillation: Survey Study


J. Stacy, Rachel Kim, Christopher D. Barrett, Balaviknesh Sekar, Steven T Simon, F. Banaei-Kashani, M. Rosenberg

JMIR Formative Research, 2022


Faculty Opinions recommendation of Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.


M. Yaffe, Christopher D. Barrett

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2021


Study of Alteplase for Respiratory Failure in SARS-CoV-2 COVID-19


Christopher D. Barrett, H. Moore, E. Moore, Janice Wang, N. Hajizadeh, W. Biffl, L. Lottenberg, Purvesh R. Patel, Michael S. Truitt, Robert McIntyre, T. Bull, L. A. Ammons, A. Ghasabyan, James G Chandler, I. Douglas, E. Schmidt, Peter K. Moore, F. Wright, Ramona Ramdeo, R. Borrego, M. Rueda, A. Dhupa, D. McCaul, Tala H Dandan, P. Sarkar, B. Khan, C. Sreevidya, Conner McDaniel, Heather M. Grossman Verner, Christopher Pearcy, L. Anez-Bustillos, Elias N. Baedorf-Kassis, Rashi Jhunjhunwala, S. Shaefi, Krystal Capers, V. Banner-Goodspeed, D. Talmor, A. Sauaia, M. Yaffe

Chest, 2021


STudy of Alteplase for Respiratory failure in SARS-Cov2 COVID-19 (STARS): A Vanguard Multicenter, Rapidly Adaptive, Pragmatic, Randomized, Controlled Trial


Christopher D. Barrett, H. Moore, E. Moore, D. J. Wang, N. Hajizadeh, W. Biffl, L. Lottenberg, Purvesh R. Patel, Michael S. Truitt, Robert McIntyre, T. Bull, L. A. Ammons, A. Ghasabyan, James G Chandler, I. Douglas, E. Schmidt, Peter K. Moore, F. Wright, Ramona Ramdeo, R. Borrego, M. Rueda, A. Dhupa, D. McCaul, Tala H Dandan, P. Sarkar, B. Khan, C. Sreevidya, Conner McDaniel, Heather M. Grossman Verner, Christopher Pearcy, L. Anez-Bustillos, Elias N. Baedorf-Kassis, Rashi Jhunjhunwala, S. Shaefi, Krystal Capers, V. Banner-Goodspeed, D. Talmor, A. Sauaia, M. Yaffe

Chest, 2021


Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model


E. Proctor, S. Dineen, Stephen C Van Nostrand, Madison K. Kuhn, Christopher D. Barrett, Douglas K. Brubaker, M. Yaffe, D. Lauffenburger, L. Leon

Journal of Thrombosis and Haemostasis, 2020


COVID-19: All the wrong moves in all the wrong places


Christopher D. Barrett, M. Yaffe

Science Signaling, 2020


Defining trauma‐induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH


H. Moore, S. Gando, T. Iba, P. Kim, C. Yeh, K. Brohi, B. Hunt, J. Levy, D. Draxler, S. Stanworth, Klaus Görlinger, M. Neal, M. Schreiber, Christopher D. Barrett, R. Medcalf, E. Moore, N. Mutch, J. Thachil, T. Urano, S. Thomas, E. Scărlătescu, M. Walsh

Journal of Thrombosis and Haemostasis, 2020


Fibrinolytic therapy for refractory COVID‐19 acute respiratory distress syndrome: Scientific rationale and review


Christopher D. Barrett, H. Moore, E. Moore, R. McIntyre, Peter K. Moore, J. Burke, F. Hua, J. Apgar, D. Talmor, A. Sauaia, D. Liptzin, L. Veress, M. Yaffe

Research and Practice in Thrombosis and Haemostasis, 2020


Influence of Tranexamic Acid on Inflammatory Signaling in Trauma


Christopher D. Barrett, Y. Kong, M. Yaffe

Seminars in Thrombosis and Hemostasis, 2020


Influence of tranexamic acid on the complement system in trauma


Christopher D. Barrett, M. Yaffe

ANZ journal of surgery, 2020


Is there a role for tissue plasminogen activator as a novel treatment for refractory COVID-19 associated acute respiratory distress syndrome?


H. Moore, Christopher D. Barrett, E. Moore, R. McIntyre, Peter K. Moore, D. Talmor, F. Moore, M. Yaffe

Journal of Trauma and Acute Care Surgery, 2020


ISTH interim guidance on recognition and management of coagulopathy in COVID‐19: A comment


Christopher D. Barrett, H. Moore, M. Yaffe, E. Moore

Journal of Thrombosis and Haemostasis, 2020


Modern Management of Bleeding, Clotting, and Coagulopathy in Trauma Patients: What Is the Role of Viscoelastic Assays?


Sanjeev Dhara, E. Moore, M. Yaffe, H. Moore, Christopher D. Barrett

Current Trauma Reports, 2020


Neutrophils, Inflammation, and Innate Immunity in Trauma-Induced Coagulopathy


Christopher D. Barrett, M. Yaffe

Trauma Induced Coagulopathy, 2020


Plasmin TEG Rapidly Identifies Trauma Patients at Risk for Massive Transfusion, Mortality and Hyperfibrinolysis: A Diagnostic Tool to Resolve an International Debate on TXA?


Christopher D. Barrett, H. Moore, N. Vigneshwar, Sanjeev Dhara, James G. Chandler, M. Chapman, A. Sauaia, E. Moore, M. Yaffe

Journal of Trauma and Acute Care Surgery, 2020


Rescue therapy for severe COVID-19–associated acute respiratory distress syndrome with tissue plasminogen activator: A case series


Christopher D. Barrett, Achikam Oren-Grinberg, Edward Chao, A. Moraco, Matthew J. Martin, Srinivas H. Reddy, A. Ilg, Rashi Jhunjhunwala, M. Uribe, H. Moore, E. Moore, Elias N. Baedorf-Kassis, M. Krajewski, D. Talmor, S. Shaefi, M. Yaffe

Journal of Trauma and Acute Care Surgery, 2020


Salvage use of tissue plasminogen activator (tPA) in the setting of acute respiratory distress syndrome (ARDS) due to COVID-19 in the USA: a Markov decision analysis


R. Choudhury, Christopher D. Barrett, H. Moore, E. Moore, R. McIntyre, Peter K. Moore, D. Talmor, T. Nydam, M. Yaffe

World Journal of Emergency Surgery, 2020


STudy of Alteplase for Respiratory failure in SARS-Cov2/COVID-19: Study Design of the Phase IIa STARS Trial


H. Moore, Christopher D. Barrett, E. Moore, Rashi Jhunjhnuwala, R. McIntyre, Peter K. Moore, Janice Wang, N. Hajizadeh, D. Talmor, A. Sauaia, M. Yaffe

2020


Study of alteplase for respiratory failure in severe acute respiratory syndrome coronavirus 2/COVID‐19: Study design of the phase IIa STARS trial


H. Moore, Christopher D. Barrett, E. Moore, Rashi Jhunjhunwala, R. McIntyre, Peter K. Moore, Janice Wang, N. Hajizadeh, D. Talmor, A. Sauaia, M. Yaffe

Research and Practice in Thrombosis and Haemostasis, 2020


Tissue plasminogen activator (tPA) treatment for COVID‐19 associated acute respiratory distress syndrome (ARDS): A case series


Janice Wang, N. Hajizadeh, E. Moore, R. McIntyre, Peter K. Moore, L. Veress, M. Yaffe, H. Moore, Christopher D. Barrett

Journal of Thrombosis and Haemostasis, 2020


Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography


Christopher D. Barrett, N. Vigneshwar, H. Moore, A. Ghasabyan, James G. Chandler, E. Moore, M. Yaffe

Blood Coagulation and Fibrinolysis, 2020


Clot activators do not expedite the time to predict massive transfusion in trauma patients analyzed with tissue plasminogen activator thrombelastography.


C. Walker, E. Moore, Adi Kam, Jacob Dexter-Meldrum, T. Nydam, M. Chapman, James G Chandler, A. Sauaia, Christopher D. Barrett, M. Yaffe, H. Moore

Surgery, 2019


Systematic Review and Meta-Analysis of Ligation vs Repair of Inferior Vena Cava (IVC) Injuries


Saskya E. Byerly, L. Tamariz, Eugenia E. Lee, J. Parreco, Christopher D. Barrett, Zsuzsanna Nemeth, A. Palacio, K. Stahl, N. Namias, G. Magee

Journal of the American College of Surgeons, 2019


Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator–dependent manner


Christopher D. Barrett, H. Moore, Y. Kong, M. Chapman, G. Sriram, D. Lim, E. Moore, M. Yaffe

Journal of Trauma and Acute Care Surgery, 2019


Modeling the Effects of Human Neutrophil Elastase on Coagulation Failure and Fibrinolysis


Christopher D. Barrett, Molly A. Bird, H. Moore, E. Moore, M. Yaffe

Journal of the American College of Surgeons, 2018


Tranexamic Acid Mediates Pro- and Anti-Inflammatory Signaling via Complement C5a Regulation in a Plasminogen Activator-Dependent Manner


Christopher D. Barrett, H. Moore, G. Sriram, D. Lim, Saskya E. Byerly, M. Chapman, E. Moore, M. Yaffe

Journal of the American College of Surgeons, 2018


Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin


Christopher D. Barrett, H. Moore, A. Banerjee, C. Silliman, E. Moore, M. Yaffe

Journal of Trauma and Acute Care Surgery, 2017


Surgical wound assessment by sonography in the prediction of surgical wound infections


Christopher D. Barrett, Arthur R. Celestin, Emily Fish, Charity C. Glass, M. Eskander, R. Murillo, Georgi Gospodinov, Alok Gupta, C. Hauser

Journal of Trauma and Acute Care Surgery, 2016


Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome


Albert T. Hsu, Christopher D. Barrett, George M DeBusk, C. Ellson, S. Gautam, D. Talmor, Diana C. Gallagher, M. Yaffe

Shock, 2015


Biomechanical Evaluation of Novel Electrospun Scaffold in a Porcine Model of Ventral Hernia Repair


C. Deeken, S. Ray, Kyle C. Ward, Christopher D. Barrett, M. Pichert, B. Eliason, Matthew R. MacEwan, M. Frisella, B. Matthews

2014

Share

Translate to